Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) (Middle Region) Peptid

Details zu Produkt Nr. ABIN981538, Anbieter: Anmelden zum Anzeigen
Proteinname
  • B830012B01
  • D530020C15Rik
  • si:zfos-979f1.3
  • pyruvate dehydrogenase kinase 1
  • pyruvate dehydrogenase kinase, isoenzyme 1
  • pyruvate dehydrogenase kinase, isozyme 1
  • pyruvate dehydrogenase kinase 1 L homeolog
  • PDK1
  • Pdk1
  • pdk1
  • pdk1.L
Protein Region
Middle Region
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-PDPK1 Antikörper (3-phosphoinositide Dependent Protein Kinase-1) (Middle Region) (ABIN2777432)
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PDK1 antibody (Catalog #: ARP31776_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: -

Protein Interaction Partner: AKT1,DLAT,PDHA1,PDK2,RPS6KB1,YWHAQ,DLAT,MTOR,PDK2,PKN1,PKN2,RALGDS,RPS6KB1,RPTOR

Protein Size: 436
Molekulargewicht 47 kDa
Gen-ID 5163
NCBI Accession NM_002610, NP_002601
UniProt Q15118
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.