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phosphodiesterase 8B (PDE8B) (Middle Region) Peptid

PDE8B Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981522
  • Target Alle PDE8B Produkte
    PDE8B (phosphodiesterase 8B (PDE8B))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    TELYSPQLGT KDEDPHTSDL VGGLMTDGLR RLSGNEYVFT KNVHQSHSHL
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PDE8B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PDE8B (phosphodiesterase 8B (PDE8B))
    Synonyme
    PDE8B Peptide, ADSD Peptide, PPNAD3 Peptide, B230331L10Rik Peptide, C030047E14Rik Peptide, RNPDE8B Peptide, phosphodiesterase 8B Peptide, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Peptide, PDE8B Peptide, LOC100468338 Peptide, pde8b Peptide, Pde8b Peptide
    Hintergrund
    The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: ADSD, FLJ11212, PPNAD3

    Protein Size: 788
    Molekulargewicht
    87 kDa
    Gen-ID
    8622
    NCBI Accession
    NM_001029851, NP_001025022
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