Nuclear RNA Export Factor 3 (NXF3) Peptid
NXF3
Reaktivität: Human, Drosophila melanogaster
Wirt: Synthetic
BP, WB
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- Target Alle NXF3 Produkte
- NXF3 (Nuclear RNA Export Factor 3 (NXF3))
- Spezies
- Human, Drosophila melanogaster
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NXF3 antibody (Catalog #: ARP40973_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NXF3 (Nuclear RNA Export Factor 3 (NXF3))
- Synonyme
- NXF3 Peptide, Gm384 Peptide, RGD1564923 Peptide, nuclear RNA export factor 3 Peptide, NXF3 Peptide, LOC523530 Peptide, LOC100060140 Peptide, LOC100060240 Peptide, LOC785244 Peptide, Nxf3 Peptide
- Hintergrund
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NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
Alias Symbols: -
Protein Interaction Partner: HNRNPUL1,NXT1,NXT2,XPO1,NUP214,NXT1,NXT2,XPO1
Protein Size: 531 - Molekulargewicht
- 60 kDa
- Gen-ID
- 56000
- NCBI Accession
- NM_022052, NP_071335
- UniProt
- Q9H4D5
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