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Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) (C-Term) Peptid

NR3C2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN980922
  • Target Alle NR3C2 Produkte
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-NR3C2 antibody (Catalog #: P100726_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Synonyme
    mr Peptide, si:ch211-189l17.1 Peptide, LOC100302443 Peptide, NR3C2 Peptide, LOC443144 Peptide, MLR Peptide, MR Peptide, MCR Peptide, NR3C2VIT Peptide, Mlr Peptide, mlr Peptide, nuclear receptor subfamily 3, group C, member 2 Peptide, nuclear receptor subfamily 3 group C member 2 Peptide, mineralocorticoid receptor Peptide, nuclear receptor subfamily 3 group C member 2 L homeolog Peptide, nr3c2 Peptide, NR3C2 Peptide, LOC443144 Peptide, Nr3c2 Peptide, nr3c2.L Peptide
    Hintergrund
    NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

    Alias Symbols: MR, MCR, MLR, FLJ41052, NR3C2VIT, MGC133092, NR3C2

    Protein Interaction Partner: ACTA1,ACTG1,AR,FKBP4,HSP90AA1,HSPA4,NR3C1,PIAS1,PIAS3,PROX1,PTGES3,TRIM24,NR3C1,PTGES3,TRIM24

    Protein Size: 867
    Molekulargewicht
    94 kDa
    Gen-ID
    4306
    NCBI Accession
    NM_001166104, NP_001159576
    UniProt
    B0ZBF5
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