NR1H4
(Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
Protein Region
Middle Region
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-NR1H4 antibody (Catalog #: ARP45626_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
NR1H4
(Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
Synonyme
zgc:110190 Peptide, zgc:92742 Peptide, NR1H4 Peptide, BAR Peptide, FXR Peptide, HRR-1 Peptide, HRR1 Peptide, RIP14 Peptide, AI957360 Peptide, Fxr Peptide, Rxrip14 Peptide, nuclear receptor subfamily 1, group H, member 5 S homeolog Peptide, nuclear receptor subfamily 1, group H, member 4 Peptide, nuclear receptor subfamily 1 group H member 4 Peptide, nr1h5.S Peptide, nr1h4 Peptide, NR1H4 Peptide, Nr1h4 Peptide
Hintergrund
NR1H4 is the receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. NR1H4 represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two d
Alias Symbols: BAR, FXR, HRR-1, HRR1, MGC163445, RIP14
Protein Interaction Partner: CASP8,ESR1,GAPDH,NCOA1,NCOR2,PPARGC1A,RXRA,RXRG,SMARCD3,CASP8,NCOA1,PPARGC1A,RXRA,SMARCD1