NR1H3
(Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-NR1H3 antibody (Catalog #: ARP38670_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
Alias Symbols: LXR-a, LXRA, RLD-1
Protein Interaction Partner: CEP350,ACTN1,EDF1,FOXO3,ING3,NCOA3,NCOA6,NCOR1,NR0B2,NRIP1,PPARA,RARA,RXRA,RXRB,RXRG,SYT1,TMEM161A,BARD1,EDF1,NR0B2,PPARA,Ppara,RXRA,SIRT1,UBC