Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Peptid
NFKB2
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle NFKB2 Produkte
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NFKB2 antibody (Catalog #: ARP32718_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
- Synonyme
- NF-kappaB2 Peptide, lyt Peptide, p49 Peptide, p49/p100 Peptide, p50B Peptide, p52 Peptide, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 Peptide, Nfkb2 Peptide
- Hintergrund
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NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Alias Symbols: p52, p105, H2TF1, LYT10, LYT-10, NF-kB2
Protein Interaction Partner: BCL3,NFKBIE,BCL3,BTRC,CHUK,DDX3X,GLG1,GTF2I,HDAC4,HDAC5,IKBKB,IKBKG,MAP3K14,MAP3K8,MEN1,NFKB1,NFKBIA,NFKBIB,NFKBIE,NKRF,NR3C1,NR5A1,PSMD11,REL,RELA,RELB,RPL30,RPL6,RPS13,TNIP2,TSC22D3,USP2,BCL3,BTRC,DDX3X,FBXW7,GLG1,IKBKG,MAP3K14,MAP3K8,MEN1,NFKB1,NFKB2,NFKBIE,NKRF,NR3C1,REL,RELA,RELB,RPL30,RPL6,RPS13,SEC16A,SP1,SUMO1,TBK1,TNIP2,TSC22D3,UBC,USP2
Protein Size: 933 - Molekulargewicht
- 101 kDa
- Gen-ID
- 4791
- NCBI Accession
- NM_002502, NP_002493
- UniProt
- Q00653
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