This is a synthetic peptide designed for use in combination with anti-NDFIP2 Antibody(ARP49441_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
NDFIP2
(Nedd4 Family Interacting Protein 2 (NDFIP2))
Synonyme
MGC68708 Peptide, DKFZp459H0627 Peptide, N4WBP5A Peptide, 0710001O20Rik Peptide, 2810436B12Rik Peptide, 9130207N19Rik Peptide, N4wbp5a Peptide, mKIAA1165 Peptide, Nedd4 family interacting protein 2 S homeolog Peptide, Nedd4 family interacting protein 2 Peptide, ndfip2.S Peptide, NDFIP2 Peptide, ndfip2 Peptide, Ndfip2 Peptide
Hintergrund
NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A
Protein Interaction Partner: ITCH,NEDD4,NEDD4L,SMURF1,WWP2,NEDD4,SLC11A2