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Nedd4 Family Interacting Protein 2 (NDFIP2) (Middle Region) Peptid

NDFIP2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN980548
  • Target Alle NDFIP2 Produkte
    NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-NDFIP2 Antibody(ARP49441_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
    Synonyme
    MGC68708 Peptide, DKFZp459H0627 Peptide, N4WBP5A Peptide, 0710001O20Rik Peptide, 2810436B12Rik Peptide, 9130207N19Rik Peptide, N4wbp5a Peptide, mKIAA1165 Peptide, Nedd4 family interacting protein 2 S homeolog Peptide, Nedd4 family interacting protein 2 Peptide, ndfip2.S Peptide, NDFIP2 Peptide, ndfip2 Peptide, Ndfip2 Peptide
    Hintergrund
    NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.

    Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A

    Protein Interaction Partner: ITCH,NEDD4,NEDD4L,SMURF1,WWP2,NEDD4,SLC11A2

    Protein Size: 336
    Molekulargewicht
    36 kDa
    Gen-ID
    54602
    NCBI Accession
    NM_019080, NP_061953
    UniProt
    Q9NV92
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