Myocyte Enhancer Factor 2A (MEF2A) (N-Term) Peptid
MEF2A
Reaktivität: Human, Drosophila melanogaster
Wirt: Synthetic
BP, WB
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- Target Alle MEF2A Produkte
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
- Protein Region
- N-Term
- Spezies
- Human, Drosophila melanogaster
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MEF2A antibody (Catalog #: ARP34223_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
- Synonyme
- ADCAD1 Peptide, RSRFC4 Peptide, RSRFC9 Peptide, mef2 Peptide, A430079H05Rik Peptide, mef2a Peptide, wu:fd19d02 Peptide, adcad1 Peptide, rsrfc4 Peptide, rsrfc9 Peptide, sl2 Peptide, MEF2A Peptide, xmef2a Peptide, myocyte enhancer factor 2A Peptide, myocyte enhancer factor 2aa Peptide, myocyte enhancer factor 2a Peptide, myocyte-specific enhancer factor 2A Peptide, myocyte-specific enhancer factor 2a, putative Peptide, myocyte enhancer factor 2A L homeolog Peptide, MEF2A Peptide, Mef2a Peptide, mef2aa Peptide, EDI_092490 Peptide, EDI_038250 Peptide, Smp_161530 Peptide, mef2a.L Peptide, mef2a Peptide, LOC539054 Peptide
- Hintergrund
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The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD, myogenin, MYF5, and MRF4 are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes.The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADCAD1, RSRFC4, RSRFC9, mef2
Protein Interaction Partner: ASCL1,CASP3,CASP7,CDK5,EP300,HDAC4,HDAC5,HDAC9,MAPK14,MAPK7,MEF2A,MEF2D,MYOD1,MYOG,PHB2,SMAD2,SMAD4,SUMO1,TEAD1,THRA,ASCL1,EP300,HDAC4,HDAC5,HDAC9,MAPK14,MAPK7,MEF2D,MYOG,SMAD2,THRA,VGLL4
Protein Size: 507 - Molekulargewicht
- 55 kDa
- Gen-ID
- 4205
- NCBI Accession
- NM_005587, NP_005578
- UniProt
- Q02078
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