Mitogen-Activated Protein Kinase 14 (MAPK14) Peptid
MAPK14
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle MAPK14 Produkte
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MAPK14 antibody (Catalog #: AVARP06004_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
- Synonyme
- CSBP Peptide, CSBP1 Peptide, CSBP2 Peptide, CSPB1 Peptide, EXIP Peptide, Mxi2 Peptide, PRKM14 Peptide, PRKM15 Peptide, RK Peptide, SAPK2A Peptide, p38 Peptide, p38ALPHA Peptide, CRK1 Peptide, Csbp1 Peptide, Csbp2 Peptide, Exip Peptide, Hog Peptide, Prkm14 Peptide, Prkm15 Peptide, Sapk2A Peptide, p38Hog Peptide, p38alpha Peptide, p38b Peptide, zp38b Peptide, MAPK14 Peptide, 186F5S Peptide, BG:DS00797.3 Peptide, CG7393 Peptide, D-p38 Peptide, D-p38 MAPK Peptide, D-p38b Peptide, Dm p38b Peptide, Dmel\\CG7393 Peptide, Dmp38b Peptide, Dp38 Peptide, Dp38b Peptide, ESTS:186F5S Peptide, Mpk34C Peptide, anon-sts23 Peptide, dp38b Peptide, p38 MAPK Peptide, p38 beta Peptide, p38B Peptide, p38Kb Peptide, p38beta Peptide, Crk1 Peptide, p38-alpha Peptide, p38MAPK Peptide, p38a Peptide, csbp Peptide, mapk14a Peptide, mxi2 Peptide, sapk2 Peptide, sapk2a Peptide, AP22.98 Peptide, AP22_98 Peptide, ATMPK14 Peptide, mitogen-activated protein kinase 14 Peptide, SAPK2a Peptide, MAP kinase 14A Peptide, MAP kinase p38a Peptide, MAPK 14A Peptide, fk28c03 Peptide, hm:zeh1243 Peptide, wu:fk28c03 Peptide, zp38a Peptide, P38C-CRK Peptide, mitogen-activated protein kinase 14 Peptide, mitogen activated protein kinase 14 Peptide, mitogen-activated protein kinase 14b Peptide, p38b MAP kinase Peptide, mitogen-activated protein kinase 14 S homeolog Peptide, mitogen-activated protein kinase 14a Peptide, CRK proto-oncogene, adaptor protein Peptide, MAPK14 Peptide, Mapk14 Peptide, mapk14b Peptide, p38b Peptide, mapk14.S Peptide, MPK14 Peptide, mapk14a Peptide, CRK Peptide
- Hintergrund
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MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA
Protein Interaction Partner: CDC25B,NCF1C,ATF2,BCL2,CDC25B,CDC25C,CDX2,CREB1,CSNK2A2,CSNK2B,DDIT3,DUSP1,DUSP10,DUSP16,DUSP2,DUSP22,DUSP4,DUSP7,DUSP9,DYRK1B,EEA1,EEF2K,EIF4EBP1,ELK1,ELK3,ESR1,FAM48A,FKBP8,FLNA,GADD45A,GMFB,GRB2,HNF4A,HSF4,HTRA2,IRAK1,JDP2,JUNB,KRT18,KRT8,MAFA,MAP2K1,MAP2K3,MAP2K4,MAP2K6,MAP3K7,MAPK1,MAPK3,MAPK8,MAPKAPK2,MAPKAPK3,MAPKAPK5,MAX,MBP,MEF2A,MEF2C,MITF,MKNK1,MKNK2,NCF1,NCOA3,NFATC1,NFATC4,NUP153,PLA2G4A,PML,PPARGC1A,PTPN7,RET,RPS6KA4,SCN8A,SHC1,SLC9A1,SMAD3,SMAD7,SPAG9,STAT1,STAT4,STK39,TAB1,TRAF6,ZFP36L1,ZFYVE20,ZNHIT1,AKT1,ATF2,ATF2,ATF2,ATF2,CDC25A,CDC25B,CDC25C,CSNK2A1,DDIT3,DUSP1,DUSP10,DUSP10,DUSP16,DUSP4,DUSP6,DYRK1B,EGFR,ELK1,ELK1,ELK4,ELK4,ETV1,FUBP1,GMFB,HTRA2,JUN,KARS,KRT8,MAP2K3,MAP2K3,MAP2K6,MAP2K7,MAPK1,MAPK14,MAPK3,MAPKAPK2,MAPKAPK3,MEF2A,MKNK1,MKNK1,PLCB2,RPS6KA3,RPS6KA4,RPS6KA5,Rps6kb1,SLC12A2,SMAD7,SPAG9,STK39,TAB1,TAB1,TGFBR1,ZFP36L1
Protein Size: 360 - Molekulargewicht
- 41 kDa
- Gen-ID
- 1432
- NCBI Accession
- NM_001315, NP_001306
- UniProt
- Q16539
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