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Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) (N-Term) Peptid

LDOC1 Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN979259
  • Target Alle LDOC1 Produkte
    LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-LDOC1 antibody (Catalog #: ARP38983_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))
    Synonyme
    BCUR1 Peptide, Mar7 Peptide, Mart7 Peptide, RGD1565644 Peptide, Gm366 Peptide, LDOC1 Peptide, LDOC1, regulator of NFKB signaling Peptide, regulator of NFKB signaling Peptide, LDOC1 Peptide, Ldoc1 Peptide
    Hintergrund
    LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

    Alias Symbols: BCUR1, Mar7, Mart7

    Protein Interaction Partner: CEBPE,MZF1,AATF,ABLIM1,AEBP2,AP1M1,ATF4,C10orf18,CCDC85B,CEBPE,DPPA4,FAM107A,FAM193B,FOSL1,FXR2,GNL3L,HGS,IKZF5,KRT15,KRT18,LNX1,MZF1,NRIP1,POLL,SMARCD1,UTP14A,ZBTB16,ZNF250,ZNF408,AATF,ABLIM1,AEBP2,AP1M1,ATF4,C10orf18,CCDC85B,DPPA4,FAM107A,FAM193B,FOSL1,FXR2,GNL3L,HGS,IKZF5,KRT15,KRT18,LNX1,NRIP1,POLL,SMARCD1,UTP14A,ZBTB16,ZNF250,ZNF408

    Protein Size: 146
    Molekulargewicht
    17 kDa
    Gen-ID
    23641
    NCBI Accession
    NM_012317, NP_036449
    UniProt
    O95751
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