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Kallikrein 6 (KLK6) Peptid

KLK6 Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN979080
  • Target Alle Kallikrein 6 (KLK6) Produkte
    Kallikrein 6 (KLK6)
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-KLK6 antibody (Catalog #: ARP33888_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Kallikrein 6 (KLK6)
    Synonyme
    Bssp Peptide, Klk7 Peptide, PRSS18 Peptide, PRSS9 Peptide, SP59 Peptide, hK6 Peptide, Prss9 Peptide, AI849898 Peptide, BSP Peptide, Klk29 Peptide, MSP Peptide, Prss18 Peptide, neurosin Peptide, kallikrein related peptidase 6 Peptide, kallikrein related-peptidase 6 Peptide, kallikrein-6 Peptide, KLK6 Peptide, Klk6 Peptide, LOC100716801 Peptide
    Hintergrund
    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

    Alias Symbols: Bssp, Klk7, MGC9355, NEUROSIN, PRSS18, PRSS9, SP59, ZYME, hK6

    Protein Interaction Partner: SERPINC1,SERPINF2,SNCA

    Protein Size: 244
    Molekulargewicht
    25 kDa
    Gen-ID
    5653
    NCBI Accession
    NM_001012964, NP_001012982
    UniProt
    Q92876
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