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Kelch-Like 3 (KLHL3) (Middle Region) Peptid

KLHL3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN979064
  • Target Alle KLHL3 Produkte
    KLHL3 (Kelch-Like 3 (KLHL3))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-KLHL3 antibody (Catalog #: ARP39277_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    KLHL3 (Kelch-Like 3 (KLHL3))
    Synonyme
    7530408C15Rik Peptide, AI430941 Peptide, EG627648 Peptide, PHA2D Peptide, RGD1565218 Peptide, kelch like family member 3 Peptide, kelch-like 3 Peptide, kelch-like family member 3 Peptide, KLHL3 Peptide, Klhl3 Peptide
    Hintergrund
    KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

    Alias Symbols: FLJ40871, KIAA1129, MGC44594, PHA2D

    Protein Interaction Partner: GNAI1,GNAO1,OPRD1,SYNCRIP,SYT2

    Protein Size: 587
    Molekulargewicht
    65 kDa
    Gen-ID
    26249
    NCBI Accession
    NM_017415, NP_059111
    UniProt
    Q9UH77
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