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Klotho beta (KLB) Peptid

KLB Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN978992
  • Target Alle Klotho beta (KLB) Produkte
    Klotho beta (KLB)
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-KLB antibody (Catalog #: ARP53325_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Klotho beta (KLB)
    Synonyme
    KLB Peptide, BKL Peptide, AV071179 Peptide, betaKlotho Peptide, Klb-ps1 Peptide, RGD1308227 Peptide, klotho beta Peptide, KLB Peptide, Klb Peptide
    Hintergrund
    KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.

    Alias Symbols: BKL, MGC142213

    Protein Interaction Partner: FGF21

    Protein Size: 1044
    Molekulargewicht
    120 kDa
    Gen-ID
    152831
    NCBI Accession
    NM_175737, NP_783864
    UniProt
    Q86Z14
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