IKBKG
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-IKBKG antibody (Catalog #: ARP30005_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males . In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito
Protein Interaction Partner: BCL10,CYLD,IKBKB,IKBKG,PRKCQ,TAB3,TANK,TRAF3IP2,TRAF3IP2,UBB,ZFAND5,tax,BCL10,BIRC3,CARD10,CARD11,CARD8,CASP8,CDC37,CHUK,COPS3,CREBBP,CYLD,FADD,GSK3B,HSP90AA1,HSP90AB1,HSPA1A,HSPA4,IKBKB,IKBKG,MAP3K14,NCOA3,NFKB1,NFKB2,NFKBIA,NFKBIB,PPM1B,PRKCQ,RAB11B,RALBP1,RIPK1,RIPK2,RNF11,SRC,TANK,TBK1,TNFAIP3,TNFRSF1A,TNIP2,TRAF3IP2,TRPC4AP,TXLNA,UBB,UBE2D3,ZFAND5,ATG16L1,BCL10,CARD8,CDC37,CHUK,CNTN2,COPS3,HSP90AA2,HSPA1A,IKBKB,IRAK1,MAP3K14,NCOA3,NFKB1,NFKB2,PPM1B,RIPK1,RIPK2,TANK,TBK1,TNFAIP3,TNFRSF1A,TRAF3IP2,TRAF6,TRPC4AP,TUBG1,UBC,ZFAND5