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Homeobox B8 (HOXB8) (N-Term) Peptid

HOXB8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978180
  • Target Alle HOXB8 Produkte
    HOXB8 (Homeobox B8 (HOXB8))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-HOXB8 antibody (Catalog #: ARP39583_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HOXB8 (Homeobox B8 (HOXB8))
    Synonyme
    HOX2 Peptide, HOX2D Peptide, Hox-2.4 Peptide, Hox2r1a Peptide, hoxa8 Peptide, z-9 Peptide, HBX Peptide, HBX24 Peptide, HOXB8 Peptide, homeobox B8 Peptide, homeobox protein Hox-B8 Peptide, homeo box B8 Peptide, homeobox B8b Peptide, porcine homeobox Peptide, HOXB8 Peptide, Hoxb8 Peptide, LOC785855 Peptide, hoxb8b Peptide, HOX-2.4 Peptide
    Hintergrund
    HOXB8 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB8 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this HOXB8 gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

    Alias Symbols: HOX2, HOX2D, Hox-2.4

    Protein Interaction Partner: MEIS1,PBX1,PBX2,PBX3,PBX1,PBX3

    Protein Size: 243
    Molekulargewicht
    28 kDa
    Gen-ID
    3218
    NCBI Accession
    NM_024016, NP_076921
    UniProt
    P17481
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