Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1) (Middle Region) Peptid
HLA-DPB1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle HLA-DPB1 Produkte
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
- Protein Region
- Middle Region
- Spezies
- Human
- Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- KRAVPDRMCR HNYELGGPMT LQRRVQPRVN VSPSKKGPLQ HHNLLVCHVT
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HLA-DPB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
- Synonyme
- PATR-DPB1 Peptide, B-LB Peptide, B-LB2 Peptide, B-LB21 Peptide, BLB1 Peptide, GSP-BLB1 Peptide, DPB1 Peptide, HLA-DP Peptide, HLA-DP1B Peptide, HLA-DPB Peptide, major histocompatibility complex, class II, DP beta 1 Peptide, Major histocompatibility complex class II beta chain BLB1 Peptide, PATR-DPB1 Peptide, BLB1 Peptide, HLA-DPB1 Peptide
- Hintergrund
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HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Alias Symbols: DPB1, HLA-DP1B
Protein Interaction Partner: CD74,HLA-DPA1,ROBO2,RTN4
Protein Size: 258 - Molekulargewicht
- 26 kDa
- Gen-ID
- 3115
- NCBI Accession
- NM_002121, NP_002112
- UniProt
- P04440
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