This is a synthetic peptide designed for use in combination with anti-Hes1 Antibody(ARP31970_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
HES1
Reaktivität: Human
Wirt: Synthetic
BP, WB, IP, IF, IHC
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
HES1
(Hes Family bHLH Transcription Factor 1 (HES1))
Synonyme
HES-1 Peptide, HHL Peptide, HRY Peptide, bHLHb39 Peptide, Hry Peptide, HAIRY1 Peptide, c-hairy1A Peptide, Xhairy1 Peptide, hairy1 Peptide, hes1 Peptide, Xhairy-1 Peptide, Xlh1 Peptide, hes family bHLH transcription factor 1 Peptide, hairy and enhancer of split 1 (Drosophila) Peptide, hes family bHLH transcription factor 4 Peptide, hes family bHLH transcription factor 1 S homeolog Peptide, hes family bHLH transcription factor 1 L homeolog Peptide, HES1 Peptide, Hes1 Peptide, HES4 Peptide, hes1.S Peptide, hes1.L Peptide
Hintergrund
Hes1 is the transcriptional repressor of genes that require a bHLH protein for their transcription. Hes1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.
Alias Symbols: Hes1
Protein Interaction Partner: Camk2a,Crebbp,Parp1,Pcaf,Polr2a,Sfpq,Src