This is a synthetic peptide designed for use in combination with anti-GTF2A1L antibody (Catalog #: ARP50819_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
ALF Peptide, 1700011N16Rik Peptide, Alf Peptide, Gtf2a1lf Peptide, general transcription factor IIA subunit 1 like Peptide, general transcription factor IIA, 1-like Peptide, general transcription factor 2A subunit 1 like Peptide, GTF2A1L Peptide, Gtf2a1l Peptide
Hintergrund
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: ALF, MGC26254
Protein Interaction Partner: ASCL3,CSNK2A1,CSNK2A2,GTF2A2,ID3,SUB1,TBP