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General Transcription Factor IIA, 1-Like (GTF2A1L) Peptid

GTF2A1L Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN977747
  • Target Alle GTF2A1L Produkte
    GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-GTF2A1L antibody (Catalog #: ARP50819_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))
    Synonyme
    ALF Peptide, 1700011N16Rik Peptide, Alf Peptide, Gtf2a1lf Peptide, general transcription factor IIA subunit 1 like Peptide, general transcription factor IIA, 1-like Peptide, general transcription factor 2A subunit 1 like Peptide, GTF2A1L Peptide, Gtf2a1l Peptide
    Hintergrund
    The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

    Alias Symbols: ALF, MGC26254

    Protein Interaction Partner: ASCL3,CSNK2A1,CSNK2A2,GTF2A2,ID3,SUB1,TBP

    Protein Size: 478
    Molekulargewicht
    52 kDa
    Gen-ID
    11036
    NCBI Accession
    NM_006872, NP_006863
    UniProt
    Q9UNN4
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