This is a synthetic peptide designed for use in combination with anti-GLI1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
GLI1
Reaktivität: Human, Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
GLI1
(Zinc Finger Protein GLI1 (GLI1))
Synonyme
GLI Peptide, Gli Peptide, Gli-1 Peptide, gli1.1 Peptide, AV235269 Peptide, Zfp-5 Peptide, Zfp5 Peptide, GLI family zinc finger 1 Peptide, GLI family zinc finger 1 S homeolog Peptide, GLI-Kruppel family member GLI1 Peptide, GLI1 Peptide, Gli1 Peptide, gli1.S Peptide, gli1 Peptide
Hintergrund
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.