V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2) Peptid
ETS2
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle ETS2 Produkte
- ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ETS2 antibody (Catalog #: P100751_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
- Synonyme
- 0123/09 Peptide, 0608/07 Peptide, 0998/12 Peptide, 3520 Peptide, CG17077 Peptide, CG8705 Peptide, D-Ets-2 Peptide, D-ets-2 Peptide, DMPOINT1A Peptide, Dmel\\CG17077 Peptide, E(E2F)3D Peptide, EK3-2 Peptide, ETS2 Peptide, EY3-1 Peptide, Ets Peptide, Ets2 Peptide, Ets58AB Peptide, Ets94F Peptide, PNT-P1 Peptide, PNTP1 Peptide, PNTP2 Peptide, POINT Peptide, Pnt Peptide, Pnt-P1 Peptide, PntP1 Peptide, PntP2 Peptide, Pointed-P1 Peptide, ets94F Peptide, l(3)07825 Peptide, l(3)j1B7 Peptide, l(3)s118306 Peptide, png Peptide, pnt-P1 Peptide, pnt-P2 Peptide, pntP2 Peptide, pntegfr Peptide, pointed-RC Peptide, ptd Peptide, zgc:92106 Peptide, wu:fe02h08 Peptide, wu:fk74c05 Peptide, AU022856 Peptide, Ets-2 Peptide, ETS2IT1 Peptide, c-ets-2 Peptide, pointed Peptide, v-ets avian erythroblastosis virus E26 oncogene homolog 2 Peptide, E26 avian leukemia oncogene 2, 3' domain Peptide, ETS proto-oncogene 2, transcription factor Peptide, pnt Peptide, ets2 Peptide, Ets2 Peptide, ETS2 Peptide
- Hintergrund
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ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ETS2IT1
Protein Interaction Partner: BRCA1,NCOA3,NCOR1,SMARCA4,SRC,TDP2,CDK10,CREBBP,EP300,ERG,ETS1,ETS2,GATA3,JUN,NCOR1,NR3C1,POU5F1,SMARCA4,SRC,STAT5B,TDP2,ZFYVE9,ZMYND11,CDK10,EP300,ERG,ETS1,FOS,JUN,NR3C1,SPI1,ZMYND11
Protein Size: 469 - Molekulargewicht
- 53 kDa
- Gen-ID
- 2114
- NCBI Accession
- NM_001127262, NP_001120734
- UniProt
- P15036
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