This is a synthetic peptide designed for use in combination with anti-EDEM1 antibody (Catalog #: ARP47054_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
zgc:55816 Peptide, edem Peptide, EDEM1 Peptide, EDEM Peptide, A130059K23Rik Peptide, mKIAA0212 Peptide, RGD1563633 Peptide, ER degradation enhancer, mannosidase alpha-like 1 Peptide, ER degradation enhancing alpha-mannosidase like protein 1 Peptide, ER degradation-enhancing alpha-mannosidase-like protein 1 Peptide, ER degradation enhancing alpha-mannosidase like protein 1 L homeolog Peptide, edem1 Peptide, EDEM1 Peptide, LOC100637820 Peptide, edem1.L Peptide, Edem1 Peptide
Hintergrund
EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.