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Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) (Middle Region) Peptid

CYP27A1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975524
  • Target Alle CYP27A1 Produkte
    CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CYP27A1 antibody (Catalog #: ARP51773_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CYP27A1 (Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))
    Synonyme
    CP27 Peptide, CTX Peptide, CYP27 Peptide, Cyp27 Peptide, P450C27 Peptide, 1300013A03Rik Peptide, cytochrome P450 family 27 subfamily A member 1 Peptide, cytochrome P450, family 27, subfamily a, polypeptide 1 Peptide, cytochrome P450, family 27, subfamily A, polypeptide 1 Peptide, sterol 26-hydroxylase, mitochondrial Peptide, CYP27A1 Peptide, Cyp27a1 Peptide, cyp27a1 Peptide
    Hintergrund
    CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CP27, CTX, CYP27

    Protein Size: 531
    Molekulargewicht
    57 kDa
    Gen-ID
    1593
    NCBI Accession
    NM_000784, NP_000775
    UniProt
    Q02318
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