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Chemokine (C-X-C Motif) Receptor 6 (CXCR6) Peptid

CXCR6 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975480
  • Target Alle CXCR6 Produkte
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CXCR6 antibody (Catalog #: AVARP07030_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    Synonyme
    BONZO Peptide, CD186 Peptide, STRL33 Peptide, TYMSTR Peptide, BB217514 Peptide, C-X-C motif chemokine receptor 6 Peptide, chemokine (C-X-C motif) receptor 6 L homeolog Peptide, chemokine (C-X-C motif) receptor 6 Peptide, CXCR6 Peptide, cxcr6.L Peptide, Cxcr6 Peptide
    Hintergrund
    CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.

    Alias Symbols: BONZO, CD186, STRL33, TYMSTR

    Protein Interaction Partner: CXCL16

    Protein Size: 342
    Molekulargewicht
    39 kDa
    Gen-ID
    10663
    NCBI Accession
    NM_006564, NP_006555
    UniProt
    O00574
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