This is a synthetic peptide designed for use in combination with anti-C19orf2 antibody (Catalog #: ARP50771_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
URI1
Reaktivität: Human, Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
URI1
(URI1, Prefoldin-Like Chaperone (URI1))
Synonyme
c19orf2 Peptide, C19orf2 Peptide, NNX3 Peptide, PPP1R19 Peptide, RMP Peptide, URI Peptide, URI1 prefoldin-like chaperone L homeolog Peptide, URI1, prefoldin like chaperone Peptide, uri1.L Peptide, URI1 Peptide
Hintergrund
The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FLJ10575, NNX3, RMP, URI, C19orf2, PPP1R19
Protein Interaction Partner: POLR2E,UXT,C19orf2,DMAP1,GTF2F2,POLR2E,STAP1,C19orf2,DMAP1,GPN1,POLR2E,RPAP2,RPAP3,RUVBL2,STAP1