ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) Peptid
ATP2A2
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle ATP2A2 Produkte
- ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ATP2A2 antibody (Catalog #: ARP45159_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
- Synonyme
- atp2b Peptide, ca-p60a Peptide, dar Peptide, serca2 Peptide, ATP2A2 Peptide, ATP2B Peptide, DAR Peptide, DD Peptide, SERCA2 Peptide, SERCA2A Peptide, ATP2 Peptide, Serca2 Peptide, SercaII Peptide, 9530097L16Rik Peptide, D5Wsu150e Peptide, SERCA2B Peptide, mKIAA4195 Peptide, atp2a2 Peptide, zgc:55380 Peptide, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 S homeolog Peptide, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Peptide, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 Peptide, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a Peptide, atp2a1.S Peptide, ATP2A2 Peptide, Atp2a2 Peptide, atp2a2a Peptide
- Hintergrund
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ATP2A2 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: ATP2B, DAR, DD, DKFZp686P0211, FLJ20293, FLJ38063, MGC45367, SERCA2
Protein Interaction Partner: ATP2A2,BCL2,CAMK2A,IRS1,IRS2,PLN,S100A1,HGS,PLN,PTP4A3,S100A1,SLN
Protein Size: 1042 - Molekulargewicht
- 115 kDa
- Gen-ID
- 488
- NCBI Accession
- NM_170665, NP_733765
- UniProt
- P16615
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