ATG4A
(Autophagy related 4A Cysteine Peptidase (ATG4A))
Protein Region
N-Term
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-ATG4A antibody (Catalog #: ARP42689_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
ATG4A
(Autophagy related 4A Cysteine Peptidase (ATG4A))
Synonyme
apg4a Peptide, autl2 Peptide, F6E13.27 Peptide, APG4A Peptide, zgc:111958 Peptide, Aut2a Peptide, AUTL2 Peptide, AI627006 Peptide, AV169859 Peptide, Apg4a Peptide, Atg4al Peptide, Autl2 Peptide, Atg4a Peptide, autophagy related 4A cysteine peptidase L homeolog Peptide, autophagy related 4A cysteine peptidase Peptide, Peptidase family C54 protein Peptide, ATG4 autophagy related 4 homolog A (S. cerevisiae) Peptide, autophagy related 4A, cysteine peptidase Peptide, atg4a.L Peptide, ATG4A Peptide, AT2G44140 Peptide, atg4a Peptide, Atg4a Peptide
Hintergrund
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.