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Argininosuccinate Lyase (ASL) Peptid

ASL Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN973513
  • Target Alle ASL Produkte
    ASL (Argininosuccinate Lyase (ASL))
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-ASL antibody (Catalog #: ARP41667_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ASL (Argininosuccinate Lyase (ASL))
    Synonyme
    ASAL Peptide, 2510006M18Rik Peptide, zgc:63532 Peptide, BA4879 Peptide, PSPTO0125 Peptide, Adl Peptide, Asl Peptide, argininosuccinate lyase Peptide, argininosuccinate lyase ArgH Peptide, adenylosuccinate lyase Peptide, argininosuccinate lyase L homeolog Peptide, ASL Peptide, Asl Peptide, asl Peptide, argH2 Peptide, argH Peptide, arg7 Peptide, CNC04420 Peptide, STHERM_c13370 Peptide, Adsl Peptide, asl.L Peptide, ARG7 Peptide
    Hintergrund
    ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

    Alias Symbols: ASAL

    Protein Interaction Partner: ASL,QARS,ASL,QARS

    Protein Size: 444
    Molekulargewicht
    49 kDa
    Gen-ID
    435
    NCBI Accession
    NM_001024944, NP_001020115
    UniProt
    P04424
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