Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (Middle Region) Peptid
ASCL1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle ASCL1 Produkte
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ASCL1 antibody (Catalog #: AVARP00017_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
- Synonyme
- ASH1 Peptide, HASH1 Peptide, MASH1 Peptide, bHLHa46 Peptide, AI225900 Peptide, Mash1 Peptide, ASCL1 Peptide, Zash-1a Peptide, ash Peptide, asha Peptide, id:ibd5085 Peptide, im:7138587 Peptide, si:dkey-264k15.2 Peptide, zash1a Peptide, zasha Peptide, Xash1 Peptide, ascl1-A Peptide, Zash-1b Peptide, ashb Peptide, zashb Peptide, achaete-scute family bHLH transcription factor 1 Peptide, achaete-scute family bHLH transcription factor 1a Peptide, achaete-scute family bHLH transcription factor 1 L homeolog Peptide, achaete-scute complex homolog 1 Peptide, achaete-scute family bHLH transcription factor 1b Peptide, ASCL1 Peptide, Ascl1 Peptide, ascl1a Peptide, ascl1.L Peptide, LOC100220505 Peptide, ascl1b Peptide
- Hintergrund
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ASCL1 may play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. ASCL1 is essential for the generation of olfactory and autonomic neurons. ASCL1 activates transcription by binding to the E box (5'-CANNTG-3').This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ASH1, HASH1, MASH1, bHLHa46
Protein Interaction Partner: ASCL1,BMP2,EP300,MEF2A,NEUROG2,TCF4,UBQLN1,EP300,MEF2A,TCF4
Protein Size: 236 - Molekulargewicht
- 25 kDa
- Gen-ID
- 429
- NCBI Accession
- NM_004316, NP_004307
- UniProt
- P50553
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