ACVRL1
(Activin A Receptor Type II-Like 1 (ACVRL1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-ACVRL1 antibody (Catalog #: ARP44199_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
ACVRL1
(Activin A Receptor Type II-Like 1 (ACVRL1))
Synonyme
ACVRL1 Peptide, vgb Peptide, alk1 Peptide, zehn1109 Peptide, hm:zehn1109 Peptide, ACVRLK1 Peptide, ALK-1 Peptide, ALK1 Peptide, HHT Peptide, HHT2 Peptide, ORW2 Peptide, SKR3 Peptide, TSR-I Peptide, R-3 Peptide, R3 Peptide, SETHKIR Peptide, AI115505 Peptide, AI427544 Peptide, Acvrlk1 Peptide, Alk1 Peptide, activin A receptor like type 1 Peptide, activin A receptor type II-like 1 Peptide, activin A receptor, type II-like 1 Peptide, ACVRL1 Peptide, acvrl1 Peptide, Acvrl1 Peptide
Hintergrund
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Alias Symbols: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Protein Interaction Partner: XIAP,ACVR2A,SNX6,TGFB1,TGFB3,TGFBR1,TGFBR2,TGFBRAP1,XIAP,SNX6,TGFB1