A synthetic peptide for use as a blocking control in assays to test for specificity of KCNS1 antibody, Alternative Names: KCNS1 control peptide, KCNS1 antibody Blocking Peptide, Anti-KCNS1 Blocking Peptide, potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 Blocking Peptide, KV9.1 Blocking Peptide, KCNS1, KCNS-1, KCNS 1, KCNS-1 Blocking Peptide, KCNS 1 Blocking Peptide
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. KCNS1 is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins.