A synthetic peptide for use as a blocking control in assays to test for specificity of SRD5 A2 antibody, Alternative Names: SRD5A2 control peptide, SRD5A2 antibody Blocking Peptide, Anti-SRD5A2 Blocking Peptide, Steroid-5-Alpha-Reductase Alpha Polypeptide 2 Blocking Peptide, 3-Oxo-5 Alpha-Steroid Delta 4-Dehydrogenase Alpha 2 Blocking Peptide, MGC138457 Blocking Peptide, SRD5A2, SRDA2-5, SRDA2 5, SRDA2-5 Blocking Peptide, SRDA2 5 Blocking Peptide
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).