A synthetic peptide for use as a blocking control in assays to test for specificity of CRYZ antibody, Alternative Names: Crystallin Zeta control peptide, Crystallin Zeta antibody Blocking Peptide, Anti-Crystallin Zeta Blocking Peptide, DKFZp779E0834 Blocking Peptide, FLJ41475 Blocking Peptide, Quinone Reductase Blocking Peptide, CRYZ Blocking Peptide
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. CRYZ is a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low.