A synthetic peptide for use as a blocking control in assays to test for specificity of CYP1 B1 antibody, Alternative Names: CYP1B1 control peptide, CYP1B1 antibody Blocking Peptide, Anti-CYP1B1 Blocking Peptide, Cytochrome P450 Family 1 Subfamily B Polypeptide 1 Blocking Peptide, CP1B Blocking Peptide, GLC3A Blocking Peptide, CYP1B1, CYPB-1, CYPB 1, CYPB-1 Blocking Peptide, CYPB 1 Blocking Peptide
CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.