A synthetic peptide for use as a blocking control in assays to test for specificity of SORD antibody, Alternative Names: SORD control peptide, SORD antibody Blocking Peptide, Anti-SORD Blocking Peptide, sorbitol dehydrogenase Blocking Peptide, SORD1 Blocking Peptide
Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.