CD22 Molecule (CD22) Peptid
CD22
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
-
- Target Alle CD22 Produkte
- CD22 (CD22 Molecule (CD22))
- Protein-Typ
- Synthetic
- Spezies
- Säugetier
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- YSALHKRQVG DYENVIPDFP EDEGIHYSEL IQFGVGERPQ AQENVDYVIL
- Produktmerkmale
-
A synthetic peptide for use as a blocking control in assays to test for specificity of CD22 antibody,
Alternative Names: CD22 control peptide, CD22 antibody Blocking Peptide, Anti-CD22 Blocking Peptide, CD22 molecule Blocking Peptide, FLJ22814 Blocking Peptide, MGC130020 Blocking Peptide, SIGLEC-2 Blocking Peptide, SIGLEC2 Blocking Peptide, CD22, CD-22, CD 22, CD-22 Blocking Peptide, CD 22 Blocking Peptide
-
-
- Applikationshinweise
- Optimal conditions should be determined by the investigator
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C long term.
-
- Target
- CD22 (CD22 Molecule (CD22))
- Synonyme
- A530093D23 Peptide, Lyb-8 Peptide, Lyb8 Peptide, SIGLEC-2 Peptide, SIGLEC2 Peptide, siglec-2 Peptide, CD22 antigen Peptide, CD22 molecule Peptide, Cd22 Peptide, CD22 Peptide
- Hintergrund
- CD22 mediates B-cell B-cell interactions. CD22 may be involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins, one of which is CD45. CD22 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response CD22 seems to be involved in regulation of B-cell antigen receptor signaling. CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
- Molekulargewicht
- 95 kDa
-
Sie sind hier:
