This is a synthetic peptide designed for use in combination with anti- RASSF8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
RASSF8
(Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))
Synonyme
c12orf2 Peptide, rassf8 Peptide, wu:fb96e06 Peptide, zgc:64017 Peptide, C12orf2 Peptide, HOJ1 Peptide, 5133400D11Rik Peptide, AA815821 Peptide, AW123240 Peptide, Hoj1 Peptide, mHoj-1 Peptide, RGD1308820 Peptide, Ras association domain family member 8 Peptide, Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b Peptide, Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 Peptide, RASSF8 Peptide, rassf8b Peptide, Rassf8 Peptide
Hintergrund
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12,22)(p11.2,q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.