This is a synthetic peptide designed for use in combination with anti- TRADD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
TRADD
(TNFRSF1A-Associated Via Death Domain (TRADD))
Synonyme
TRADD Peptide, Hs.89862 Peptide, 9130005N23Rik Peptide, AA930854 Peptide, wu:fc59e02 Peptide, zgc:103556 Peptide, tradd Peptide, TNFRSF1A associated via death domain Peptide, conjugal transfer protein D Peptide, TNFRSF1A-associated via death domain Peptide, TNFRSF1A-associated via death domain L homeolog Peptide, tnfrsf1a-associated via death domain Peptide, TRADD Peptide, traDd Peptide, Tradd Peptide, tradd.L Peptide, tradd Peptide
Hintergrund
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.