Protein Arginine Methyltransferase 6 (PRMT6) (N-Term) Peptid
PRMT6
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle PRMT6 Produkte
- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- KLESGGGGEG GEGTEEEDGA EREAALERPR RTKRERDQLY YECYSDVSVH
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- PRMT6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
- Synonyme
- CG9927 Peptide, DART6 Peptide, Dmel\\CG9927 Peptide, PRMT6 Peptide, HRMT1L6 Peptide, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6 Peptide, ATPRMT6 Peptide, protein arginine methyltransferase 6 Peptide, DKFZp459B1431 Peptide, Hrmt1l6 Peptide, hrmt1l6 Peptide, hrmt6 Peptide, im:6908706 Peptide, AW124876 Peptide, BB233495 Peptide, Arginine methyltransferase 6 Peptide, protein arginine methyltransferase 6 Peptide, protein arginine methyltransferase 6 S homeolog Peptide, arginine N-methyltransferase, type I Peptide, protein arginine N-methyltransferase 6 Peptide, Art6 Peptide, PRMT6 Peptide, prmt6.S Peptide, prmt6 Peptide, Prmt6 Peptide
- Hintergrund
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The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Alias Symbols: HRMT1L6
Protein Size: 292 - Gen-ID
- 55170
- NCBI Accession
- NM_018137, NP_060607
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