This is a synthetic peptide designed for use in combination with anti- NCBP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
NCBP1
Reaktivität: Human, Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
NCBP1
(Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))
Synonyme
CBP80 Peptide, CG7035 Peptide, Dmel\\CG7035 Peptide, EG:84H4.3 Peptide, ncbp Peptide, sto1 Peptide, cbp80 Peptide, AU014645 Peptide, AW538051 Peptide, NCBP Peptide, Sto1 Peptide, ncbp1 Peptide, ABA HYPERSENSITIVE 1 Peptide, ATCBP80 Peptide, CAP-BINDING PROTEIN 80 Peptide, ENS Peptide, ENSALADA Peptide, NUCLEAR CAP-BINDING PROTEIN CBP80 Peptide, T10F5.8 Peptide, T10F5_8 Peptide, cap binding protein 80 Peptide, nuclear cap binding protein subunit 1 Peptide, nuclear cap binding protein subunit 1 S homeolog Peptide, nuclear cap binding protein subunit 1, 80kDa Peptide, nuclear cap binding protein subunit 1 L homeolog Peptide, ARM repeat superfamily protein Peptide, Nuclear cap-binding protein subunit 1-A Peptide, Nuclear cap-binding protein subunit 1 Peptide, Cbp80 Peptide, ncbp1 Peptide, ncbp1.S Peptide, NCBP1 Peptide, Ncbp1 Peptide, ncbp1.L Peptide, ABH1 Peptide, nbp1a Peptide, ncbp-1 Peptide
Hintergrund
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.