Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

IgG3 (Middle Region) Peptid

Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN5671649
  • Target Alle IgG3 Produkte
    IgG3
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Western Blotting (WB), Blocking Peptide (BP)
    Sequenz
    TKNQVSLTCL VKGFYPSDIA VEWESSGQPE NNYNTTPPML DSDGSFFLYS
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- IGHG3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IgG3
    Synonyme
    IgG3 Peptide, Immunoglobulin heavy constant gamma 3 Peptide, immunoglobulin heavy constant gamma 3 (G3m marker) Peptide, Ighg3 Peptide, IGHG3 Peptide
    Substanzklasse
    Antibody
    Hintergrund
    Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

    Alias Symbols: IgG3

    Protein Size: 377
    Gen-ID
    3502
    UniProt
    P01860
Sie sind hier:
Kundenservice