This is a synthetic peptide designed for use in combination with anti- COL2A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
COL2A1
(Collagen, Type II, alpha 1 (COL2A1))
Synonyme
ANFH Peptide, AOM Peptide, COL11A3 Peptide, SEDC Peptide, Col2 Peptide, Col2a Peptide, Col2a-1 Peptide, Del1 Peptide, Dmm Peptide, Lpk Peptide, M100856 Peptide, Rgsc856 Peptide, CG2A1A Peptide, COLLII Peptide, col2a1a Peptide, CB11 Peptide, col2a1 Peptide, coll2a1 Peptide, fb38c06 Peptide, fc10c01 Peptide, wu:fb38c06 Peptide, wu:fc10c01 Peptide, collagen type II alpha 1 chain Peptide, collagen, type II, alpha 1 Peptide, collagen, type II, alpha 1 L homeolog Peptide, collagen, type II, alpha 1 S homeolog Peptide, collagen, type II, alpha 1a Peptide, COL2A1 Peptide, Col2a1 Peptide, col2a1 Peptide, col2a1.L Peptide, col2a1.S Peptide, col2a1a Peptide
Hintergrund
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.