Mismatch Repair Protein 2 (MSH2) (Middle Region) Peptid
MSH2
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle MSH2 Produkte
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- AQFGYYFRVT CKEEKVLRNN KNFSTVDIQK NGVKFTNSKL TSLNEEYTKN
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- MSH2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Synonyme
- COCA1 Peptide, FCC1 Peptide, HNPCC Peptide, HNPCC1 Peptide, LCFS2 Peptide, AI788990 Peptide, wu:fc06b02 Peptide, wu:fc13e09 Peptide, zgc:55333 Peptide, ATMSH2 Peptide, MUTS homolog 2 Peptide, msh2 Peptide, mutS homolog 2 Peptide, mutS homolog 2 (E. coli) Peptide, MUTS homolog 2 Peptide, mutS homolog 2 L homeolog Peptide, MutS protein homolog 2 Peptide, MSH2 Peptide, Msh2 Peptide, msh2 Peptide, msh2.L Peptide
- Hintergrund
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This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FCC1, COCA1, HNPCC, LCFS2, HNPCC1
Protein Size: 934 - Gen-ID
- 4436
- NCBI Accession
- NM_000251, NP_000242
- UniProt
- P43246
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