×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (Middle Region) Peptid
SHC1
Reaktivität: Human
Wirt: Synthetic
WB
Produktnummer ABIN5518203
Produktdetails
(ausblenden)
Target
Alle SHC1 Produkte
SHC1
(SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
Protein Region
Middle Region
Spezies
Human
Quelle
Alle Wirte für SHC1 Peptide
Synthetic
Applikation
Western Blotting (WB)
Sequenz
EPPDHQYYND FPGKEPPLGG VVDMRLREGA APGAARPTAP NAQTPSHLGA
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigendetails
(ausblenden)
Target
SHC1
(SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
Synonyme
SHC1 Peptide, SHC Peptide, SHCA Peptide, P66shc Peptide, si:dkey-246i14.4 Peptide, wu:fc10h03 Peptide, shc Peptide, p66shc Peptide, Shc Peptide, ShcA Peptide, p66 Peptide, SHC adaptor protein 1 Peptide, Shc1p Peptide, squalene--hopene cyclase Peptide, SHC (Src homology 2 domain containing) transforming protein 1 Peptide, SHC (Src homology 2 domain containing) transforming protein 1 L homeolog Peptide, src homology 2 domain-containing transforming protein C1 Peptide, SHC1 Peptide, shc1 Peptide, Shc1 Peptide, shc1.L Peptide
Hintergrund
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. Alias Symbols: SHC, SHCA Protein Size: 167
Gen-ID
6464
NCBI Accession
NM_001130040 , NP_001123512
UniProt
P29353
Zuletzt angesehen
(ausblenden)
Sie sind hier:
Startseite
Peptide
SHC1
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) (Middle Region) Peptid (ABIN5518203)