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Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) (N-Term) Peptid

CYP3A4 Reaktivität: Human Wirt: Synthetic WB
Produktnummer ABIN5518122
  • Target Alle CYP3A4 Produkte
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 11
    Synthetic
    Applikation
    Western Blotting (WB)
    Sequenz
    LFKKLGIPGP TPLPFLGNIL SYHKGFCMFD MECHKKYGKV WGFYDGQQPV
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Synonyme
    CP33 Peptide, CP34 Peptide, CYP3A Peptide, CYP3A3 Peptide, CYPIIIA3 Peptide, CYPIIIA4 Peptide, HLP Peptide, NF-25 Peptide, P450C3 Peptide, P450PCN1 Peptide, MGC108372 Peptide, CYP3A80 Peptide, CYP3A4 Peptide, CYP3A21 Peptide, CYPIIIA21 Peptide, CYP3A12 Peptide, cytochrome P450 family 3 subfamily A member 4 Peptide, cytochrome P450 family 3 subfamily A member 43 Peptide, cytochrome P450 3A4 Peptide, cytochrome P450, subfamily IIIA, polypeptide 4 Peptide, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 Peptide, cytochrome P450, family 3, subfamily A, polypeptide 4 Peptide, CYP3A4 Peptide, CYP3A43 Peptide, PTRG_01782 Peptide, PTRG_06060 Peptide, cyp3a4 Peptide
    Hintergrund
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Alias Symbols: HLP, CP33, CP34, CYP3A, NF-25, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1,

    Protein Size: 167
    Gen-ID
    1576
    NCBI Accession
    NM_001202855, NP_001189784
    UniProt
    P08684
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