This is a synthetic peptide designed for use in combination with anti-C1QL3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
C1QL3 may regulate the number of excitatory synapses that are formed on hippocampus neurons. It has no effect on inhibitory synapses . It plays a role in glucose homeostasis. Via AMPK signaling pathway, C1QL3 stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, C1QL3 reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production.