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Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (Middle Region) Peptid

GZMH Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513040
  • Target Alle GZMH Produkte
    GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    RDDFVLTAAH CWGSSINVTL GAHNIKEQEP TQQFIPVKRP IPHPAYNPKN
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-GZMH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
    Synonyme
    GZMH Peptide, CCP-X Peptide, CGL-2 Peptide, CSP-C Peptide, CTLA1 Peptide, CTSGL2 Peptide, granzyme H Peptide, LOC617313 Peptide, GZMH Peptide
    Hintergrund
    This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.

    Alias Symbols: CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2

    Protein Size: 160
    Gen-ID
    2999
    NCBI Accession
    NM_001270781, NP_001257710
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