Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) (N-Term) Peptid
CHRNA10
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CHRNA10 Produkte
- CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- GGLDAIRIPS SLVWRPDIVL YNKADAQPPG SASTNVVLRH DGAVRWDAPA
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CHRNA10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
- Synonyme
- si:dkey-24p1.3 Peptide, ALPHA 10 nAChR Peptide, cholinergic receptor, nicotinic, alpha polypeptide 10 Peptide, cholinergic receptor nicotinic alpha 10 subunit Peptide, cholinergic receptor, nicotinic, alpha 10a Peptide, neuronal acetylcholine receptor subunit alpha-10 Peptide, cholinergic receptor, nicotinic, alpha 10 (neuronal) Peptide, Chrna10 Peptide, CHRNA10 Peptide, chrna10a Peptide, LOC100344381 Peptide
- Hintergrund
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CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
Alias Symbols: CHRNA10,NACHRA10,
Protein Size: 450 - Gen-ID
- 57053
- NCBI Accession
- NP_065135
- UniProt
- Q9GZZ6
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