This is a synthetic peptide designed for use in combination with anti-AP2M1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
AP2M1
(Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
Synonyme
AP50 Peptide, CLAPM1 Peptide, mu2 Peptide, Ap50 Peptide, Clapm1 Peptide, cb34 Peptide, Ap2m1 Peptide, dpy-23 Peptide, sb:cb34 Peptide, zgc:55711 Peptide, zgc:85653 Peptide, wu:fa97a10 Peptide, ap2m1-a Peptide, ap2m1 Peptide, zgc:56643 Peptide, AP2M1 Peptide, adaptor related protein complex 2 mu 1 subunit Peptide, adaptor-related protein complex 2, mu 1 subunit Peptide, adaptor-related protein complex 2, mu 1 subunit, a Peptide, adaptor related protein complex 2 mu 1 subunit L homeolog Peptide, adaptor-related protein complex 2, mu 1 subunit, b Peptide, AP-2 complex subunit mu-1 Peptide, clathrin coat assembly protein AP50 Peptide, clathrin coat assembly protein ap50 Peptide, AP2M1 Peptide, Ap2m1 Peptide, ap2m1a Peptide, ap2m1.L Peptide, ap2m1b Peptide, ap2m1 Peptide, cgd8_950 Peptide, PY06523 Peptide, PVX_118455 Peptide, PVX_123590 Peptide, CpipJ_CPIJ003697 Peptide
Hintergrund
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene.