This is a synthetic peptide designed for use in combination with anti-GET4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
Chromosome 7 Open Reading Frame 20 (C7orf20)
Synonyme
cee Peptide, cgi-20 Peptide, c7orf20 Peptide, get4 Peptide, C7orf20 Peptide, CEE Peptide, TRC35 Peptide, 1110007L15Rik Peptide, AW412535 Peptide, Cee Peptide, RGD1311660 Peptide, C25H7ORF20 Peptide, get4-a Peptide, golgi to ER traffic protein 4 Peptide, chromosome 7 open reading frame 20 Peptide, Cee Peptide, golgi to ER traffic protein 4 homolog (S. cerevisiae) Peptide, golgi to ER traffic protein 4 S homeolog Peptide, get4 Peptide, Bm1_33940 Peptide, LOC100136505 Peptide, GET4 Peptide, Get4 Peptide, get4.S Peptide
Hintergrund
GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.